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Clinical History:
18 year old male with complex, enhancing
mass in the posterior aspect of the left kidney
found incidentally on imaging
done post-traumatic fall evaluation. Mom has been
diagnosed with cerebrovascular malformations.
Histology: Figure A shows
moderately to markedly irregular nuclear contours with
visible nucleoli (Fuhrman grade 3).
Special IHC show tumor cells with diffuse cytoplasmic
and cell membrane staining for e-cadherin, patchy
staining for RCC. Colloidal iron staining is also
negative in the tumor cells. This tumor antigenic
profile is not characteristic of any of the classified
renal cell carcinomas, with the closest possibility of a
papillary type with mixed features of clear cells and
oncocytic cells. |
